ISRO had the benefit of International cooperation since inception.

Establishment of TERLS, conduct of SITE & STEP, launches of Aryabhata, Bhaskara, APPLE, IRS-IA and IRS-IB/ satellites manned space mission, etc involved international cooperation.

ISRO operates LUT/MCC under international COSPAS/SARSAT Programme for Search and Rescue.

MOU now exists with Canada, China, European Space Agency, France, Germany, Hungary, Indonesia, Mauritius, Norway, Russia, Sweden, Syria, The Netherlands and Ukraine.

India has established a Center for Space Science and Technology Education in Asia and the Pacific (CSSTE-AP) that is sponsored by United Nations.

India Hosted the Second UN-ESCAP Ministerial Conference on Space Applications for Sustainable Development in Asia and the Pacific in November 1999.